Keywords: Core International Biotech Company Ltd., SMPPT, BAISHIHUAQI, Small Molecule Peptides, Milk Small Molecule Peptides

After a year-long evaluation and clinical feedback, Guangzhou Core International Biotech Company Ltd. (C.I. Biotech Co. Ltd.) launched the first milk SMPPT (small molecule peptide) to give cell nutrition and anti-aging in Australia in the 24th last month. Using the high bio-activity of SMPPT, C.I. Biotech Co. Ltd. has created the international brand BAISHIHUAQI, a brand based on natural and gentle ingredients to target human skin health problems.

Rigorous scientific experiments have proven that SMPPT is a breakthrough ingredient in giving nutrients to cells and fighting against early-state aging. Dr. Herber Boyer, at the University of California, studied small molecule peptides for 38 years and proposed in 1958 that SMPPT has the ability to provide nutrients to cells and improve human immunity. In the following decades, MIT and other world-leading research institutions confirmed that SMPPT can regulate Ca2+ re-absorption, reduce the synthesis of Aβ protein, and improve the cellular micro-environment, along with many other effects.

Acting Mechanism of SMPPT (BAISHIHUAQI core ingredient) on muscle cells and others

These findings have made SMPPT a research hot-spot in the medical community, and the categories of SMPPT contained drugs are currently more than one hundred varieties, involving more than ten fields such as gastrointestinal, bone and connective tissue, cardiovascular, hematological, oncological, and neurological. In just a few years, nearly one hundred relevant papers have been published in high-impact academic journals such as CELL, NATURE, and SCIENCE, which have explored and elaborated the function and application of SMPPT.

These studies found that SMPPT can promote the synthesis of collagen and hyaluronic acid in skin fibroblasts, giving cells nutrition and effectively delaying skin aging caused by D-galactose, and thus improving skin elasticity. Verified by FOOD SCIENCE, a journal included in EI Compendex, due to its small molecular and high bio-availability, SMPPT is easily digested and absorbed by human body, and therefore is able to repair degenerated cells and maintain normal cell metabolism.

Schematic diagram of SMPPT repairing damaged cells

In 1986, Nobel Laureate Rita Levi-Montalcini believed that the discovery of nerve growth factor  to be of epochal importance in the field of medical cosmetology. SMPPT is a significant component of nerve growth factor, and has been commonly used in the high-end lines of many major international brands as a new ingredient in the cosmetic industry since the 20th century.

Structure diagram of growth factor

Although SMPPT has received intensive attention for the past few years, it remains as a great challenge to popularize SMPPT products to plain folks. According to the journal Guangzhou Chemical Industry, 90% of SMPPT currently available in the market are obtained by traditional chemical synthesis, which is tedious, time-consuming, and low in success rate, consequently causing high cost. Besides, chemical synthesis reactions are highly dependent on the peptide chain sequence, i.e. as the complexity of the peptide chain increases, it is beyond the ability of the traditional chemical synthetic methods to obtain both multifarious and bio-active SMPPT.

Schematic diagram of protein isolation of multiple potent small molecule peptides

Hence, despite that SMPPT has received the attention from many researchers, the lack of mature producing technology makes it difficult to mass production, limiting the advanced technological achievements of SMPPT to very few people only. In order to make up for such shortcoming, C.I. Biotech Co. Ltd. has brought the bio-enzymatic cutting technology into the industry field of fine chemicals, and established the international brand BAISHIHUAQI that mainly formulating natural and mild ingredients, leading SMPPT to increasing popularity.

The predecessor of C.I. Biotech Co. Ltd., who has successfully commercialized SMPPT at this time, was founded in 1993, and its core members come from top biotechnology institutions and pharmaceutical research institutes in the UK, the US, Australia, and Hong Kong. It is reported that the high bio-active SMPPT nutrient solution that has been successfully refined by C.I. Biotech Co. Ltd. can more effectively provide nutrition to cells due to its small size of molecule, leading to greater biologically penetrating properties, thus can better maintain normal cell metabolism and repair degenerated cells.

Schematic diagram of the bioluminescence technology (technological breakthrough by BAISHIHUAQI )

The successful application of this bio-enzymatic cutting method in the domestic biotechnological field has promoted the large-scale production of SMPPT and in return reduced the production cost, giving more people access to products containing highly bio-active SMPPT and enabling more people to enjoy the fruits of the technological revolution.

It is understood that the full marketability of SMPPT products is still facing some uncertainties. Based on the powerful repair function of the highly bio-active ingredient SMPPT on damaged skin cells, there have been attempts by pharmaceutical companies to apply for SMPPT as a prescription drug for medical cosmetology, making SMPPT products available to consumers only through doctors' prescriptions, thus monopolizing the sale of SMPPT products. In addition, some social ethicists have expressed concerns about the popularity of such highly effective anti-aging products and have suggested that such products should be regulated.

In any case, the launch of SMPPT products shows that with the continuous development of science and technology, mankind can give greater confidence in the fight against early-state aging. Perhaps, the dream of retaining youth can be realized？